XRCC5 Antikörper

Produktnummer ABIN6570166

Produktdetails anti-XRCC5 Antikörper

Target: XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XRCC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human XRCC5 (NP_066964.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:100-1:200 IF 1:20-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu XRCC5

Target: XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))

Andere Bezeichnung: XRCC5 (XRCC5 Produkte)

Synonyme: AI314015 antikoerper, Ku80 antikoerper, Ku86 antikoerper, Kup80 antikoerper, KARP-1 antikoerper, KARP1 antikoerper, KU80 antikoerper, KUB2 antikoerper, NFIV antikoerper, xrcc5-a antikoerper, XRCC5 antikoerper, X-ray repair cross complementing 5 antikoerper, X-ray repair complementing defective repair in Chinese hamster cells 5 antikoerper, X-ray repair complementing defective repair in Chinese hamster cells 5 L homeolog antikoerper, XRCC5 antikoerper, Xrcc5 antikoerper, xrcc5.L antikoerper

Hintergrund: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Molekulargewicht:

Observed_MW: 100kDa

Calculated_MW: 82kDa

Gen-ID: 7520

UniProt: P13010

Pathways: DNA Reparatur