CDK2AP1 Antikörper

Produktnummer ABIN6569649

Produktdetails anti-CDK2AP1 Antikörper

Target: CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK2AP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human CDK2AP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CDK2AP1

Target: CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))

Andere Bezeichnung: DOC1 (CDK2AP1 Produkte)

Synonyme: MGC64532 antikoerper, doc1 antikoerper, st19 antikoerper, doc-1 antikoerper, dorc1 antikoerper, p12doc-1 antikoerper, Apc10 antikoerper, Cdkap1 antikoerper, DORC1 antikoerper, Doc1 antikoerper, ST19 antikoerper, p12 antikoerper, DOC1 antikoerper, p12DOC-1 antikoerper, cyclin-dependent kinase 2 associated protein 1 S homeolog antikoerper, cyclin dependent kinase 2 associated protein 1 antikoerper, cyclin dependent kinase 2 associated protein 1 pseudogene antikoerper, cyclin-dependent kinase 2 associated protein 1 antikoerper, CDK2 (cyclin-dependent kinase 2)-associated protein 1 antikoerper, cdk2ap1.S antikoerper, CDK2AP1 antikoerper, LOC475806 antikoerper, cdk2ap1 antikoerper, Cdk2ap1 antikoerper

Hintergrund:

Synonyms: CDK2 A1,CDK2 associated protein 1,CDK2-associated protein 1,CDK2AP1,CDKA1,CDKA1,Cyclin dependent kinase 2 associated protein 1,Cyclin-dependent kinase 2-associated protein 1,Deleted in oral cancer 1,DOC 1,DOC 1 related protein,DOC 1R,DOC-1,DOC1,DOC1R,DORC1,p12DOC 1,Putative oral cancer suppressor,ST19

Background: The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molekulargewicht:

Observed_MW: 12kDa

Calculated_MW: 9kDa/12kDa

Gen-ID: 8099

UniProt: O14519