N-Myc Downstream Regulated 1 (NDRG1) Antikörper

Details zu Produkt Nr. ABIN6569133
Target
Reaktivität
Human, Maus
123
59
45
6
4
3
3
3
3
2
2
2
2
2
1
Wirt
Kaninchen
96
22
8
2
Klonalität
Polyklonal
Konjugat
Unkonjugiert
9
5
5
5
4
4
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
95
46
37
31
25
18
17
4
4
3
3
2
1
1
1
Optionen
Immunogen Recombinant protein of human NDRG1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung NDRG1 (NDRG1 Antibody Abstract)
Hintergrund

Synonyms: 42 kDa,Anti GC4,cap43,cmt4d,Differentiation related gene1 protein,Differentiation-related gene 1 protein,Drg 1,DRG-1,drg1,gc4,GC4,hmsnl,Human mRNA for RTP complete cds,N myc downstream regulated gene 1,N myc downstream regulated gene 1 protein,N-myc downstream-regulated gene 1 protein,Ndr 1,ndr1,NDRG 1,Ndrg1,NDRG1 protein,NDRG1,Nickel specific induction protein,Nickel specific induction protein Cap43,Nickel-specific induction protein Cap43,nmsl,Nmyc downstream regulated,Nmyc downstream regulated gene1,Nmyc downstream regulated gene1 protein,Protein NDRG1,Protein regulated by oxygen 1,Protein regulated by oxygen1,Proxy1,Reduced in tumor,Reducin,Reducing agents and tunicamycin responsive protein,Reducing agents and tunicamycin-responsive protein,Rit42,RTP,targ1,TDD5,tdds,Tunicamycin responsive protein

Background: This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molekulargewicht

Observed_MW: 48kDa

Calculated_MW: 33kDa/35kDa/42kDa

Gen-ID 10397
UniProt Q92597
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-N-Myc Downstream Regulated 1 (NDRG1) antibody (ABIN6569133) Immunofluorescence analysis of U2OS cells using NDRG1 antibody.
Image no. 2 for anti-N-Myc Downstream Regulated 1 (NDRG1) antibody (ABIN6569133) Western blot analysis of extracts of various cell lines, using NDRG1 antibody.