IL1RN Antikörper (Interleukin 1 Receptor Antagonist)

Details for Product anti-IL1RN Antibody No. ABIN6569095
Target
Reaktivität
Human, Maus
96
36
32
10
10
9
7
4
4
4
3
Wirt
Kaninchen
110
43
5
3
3
1
Klonalität
Polyklonal
Konjugat
Dieser IL1RN Antikörper ist unkonjugiert
31
24
4
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
123
61
55
30
24
23
18
15
14
13
11
8
8
3
2
1
1
1
1
1
Optionen
Immunogen Recombinant protein of human IL1RN
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung IL1RN (IL1RN Antibody Abstract)
Hintergrund

Synonyms: DIRA,F630041P17Rik,ICIL 1RA,ICIL-1RA,ICIL1RA,IL-1ra,IL-1ra3,IL-1RN,IL1 inhibitor,IL1F3,IL1RA,IL1RA,IL1RN (IL1F3),IL1RN,Interleukin 1 receptor antagonist,Interleukin-1 receptor antagonist protein,Intracellular IL 1 receptor antagonist type II,Intracellular interleukin 1 receptor antagonist (icIL 1ra),IRAP,MGC10430,MVCD4,Type II interleukin 1 receptor antagonist

Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.

Molekulargewicht

Observed_MW: 23kDa

Calculated_MW: 16kDa/17kDa/19kDa/20kDa

Gen-ID 3557
UniProt P18510
Pathways NF-kappaB Signalweg, Hormone Transport, Cancer Immune Checkpoints
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Interleukin 1 Receptor Antagonist (IL1RN) antibody (ABIN6569095) Immunofluorescence analysis of MCF-7 cells using IL1RN antibody.
Image no. 2 for anti-Interleukin 1 Receptor Antagonist (IL1RN) antibody (ABIN6569095) Western blot analysis of extracts of various cell lines, using IL1RN antibody.