HCK Antikörper (Hemopoietic Cell Kinase)

Details for Product anti-HCK Antibody No. ABIN6569091
Target
Reaktivität
Human, Maus
96
43
31
1
1
1
1
1
Wirt
Kaninchen
84
12
1
Klonalität
Polyklonal
Konjugat
Dieser HCK Antikörper ist unkonjugiert
7
6
6
5
5
5
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
76
58
31
17
13
12
8
3
2
2
2
1
1
Optionen
Immunogen Recombinant protein of human HCK
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung HCK (HCK Antibody Abstract)
Hintergrund

Synonyms: Bmk,Hck 1,Hck,HCK,Hemopoietic cell kinase,JTK9,p59-HCK/p60-HCK,p59Hck,p59HCK/p60HCK,p61Hck,Tyrosine protein kinase HCK,Tyrosine-protein kinase HCK

Background: The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.

Molekulargewicht

Observed_MW: 65kDa

Calculated_MW: 57kDa/59kDa

Gen-ID 3055
UniProt P08631
Pathways Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
Applikations-hinweise WB 1:500 - 1:2000 IF 1:10 - 1:100
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Hemopoietic Cell Kinase (HCK) antibody (ABIN6569091) Immunofluorescence analysis of A549 cells using HCK antibody.
Image no. 2 for anti-Hemopoietic Cell Kinase (HCK) antibody (ABIN6569091) Western blot analysis of extracts of HL-60 cells, using HCK antibody.