DCK Antikörper (Deoxycytidine Kinase)

Details for Product anti-DCK Antibody No. ABIN6568902
Target
Reaktivität
Human, Maus, Ratte
68
38
19
3
3
2
2
2
2
1
1
1
1
Wirt
Kaninchen
57
13
3
Klonalität
Polyklonal
Konjugat
Dieser DCK Antikörper ist unkonjugiert
5
5
3
2
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
59
34
27
26
26
13
11
5
3
2
2
1
1
1
1
Optionen
Immunogen Recombinant protein of human DCK
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung DCK (DCK Antibody Abstract)
Hintergrund

Synonyms: dCK,DCK protein,DCK,Deoxycytidine kinase,Deoxynucleoside kinase,EC 2.7.1,EC 2.7.1.74,MGC117410,MGC138632,OTTHUMP00000219118,OTTHUMP00000219119

Background: Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.

Molekulargewicht

Observed_MW: 31kDa

Calculated_MW: 30kDa

Gen-ID 1633
UniProt P27707
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Deoxycytidine Kinase (DCK) antibody (ABIN6568902) Immunohistochemistry of paraffin-embedded human vermiform appendix using DCK antibody.
Image no. 2 for anti-Deoxycytidine Kinase (DCK) antibody (ABIN6568902) Western blot analysis of extracts of various cell lines, using DCK Antibody.
Image no. 3 for anti-Deoxycytidine Kinase (DCK) antibody (ABIN6568902) Immunohistochemistry of paraffin-embedded rat kidney using DCK antibody.
Image no. 4 for anti-Deoxycytidine Kinase (DCK) antibody (ABIN6568902) Immunofluorescence analysis of HeLa cells using DCK antibody.