XRCC4 Antikörper (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4)

Details for Product anti-XRCC4 Antibody No. ABIN6568844
Target
Reaktivität
Human, Maus, Ratte
81
27
26
2
2
2
2
1
1
1
1
1
1
Wirt
Kaninchen
73
8
Klonalität
Polyklonal
Konjugat
Dieser XRCC4 Antikörper ist unkonjugiert
5
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
56
26
15
13
11
9
7
4
2
1
1
1
Optionen
Immunogen Recombinant protein of human XRCC4
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung XRCC4 (XRCC4 Antibody Abstract)
Hintergrund

Synonyms: DNA double strand break repair and V(D)J recombination protein XRCC4,DNA repair protein XRCC4,SSMED,X ray repair complementing defective repair in Chinese hamster cells 4,X ray repair cross complementing 4,X ray repair cross complementing protein 4,X-ray repair cross-complementing protein 4,XRCC 4,XRCC4,XRCC4

Background: The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.

Molekulargewicht

Observed_MW: 45kDa

Calculated_MW: 35kDa/38kDa

Gen-ID 7518
UniProt Q13426
Pathways DNA Reparatur, Production of Molecular Mediator of Immune Response
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4) antibody (ABIN6568844) Western blot analysis of extracts of various cell lines, using XRCC4 antibody.
Image no. 2 for anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4) antibody (ABIN6568844) Immunohistochemistry of paraffin-embedded rat pancreas using XRCC4 Antibody.
Image no. 3 for anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4) antibody (ABIN6568844) Immunohistochemistry of paraffin-embedded human gastric cancer using XRCC4 Antibody.
Image no. 4 for anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4) antibody (ABIN6568844) Immunofluorescence analysis of U2OS cells using XRCC4 antibody.