TFPI Antikörper (Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor))

Details for Product anti-TFPI Antibody No. ABIN6568810
Target
Reaktivität
Human, Maus
96
40
37
7
3
2
2
2
2
1
Wirt
Kaninchen
77
28
7
5
3
1
Klonalität
Polyklonal
Konjugat
Dieser TFPI Antikörper ist unkonjugiert
16
10
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
85
47
34
22
13
12
11
8
7
4
4
4
2
1
1
1
1
Optionen
Immunogen Recombinant protein of human TFPI
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung TFPI (TFPI Antibody Abstract)
Hintergrund

Synonyms: Anti convertin,EPI,Extrinsic pathway inhibitor,LACI,Lipoprotein associated coagulation inhibitor,Lipoprotein-associated coagulation inhibitor,TFI,TFPI 1,TFPI,TFPI1,TFPI1,Tissue factor pathway inhibitor (lipoprotein associated coagulation inhibitor),Tissue factor pathway inhibitor

Background: This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed.

Molekulargewicht

Observed_MW: 31kDa

Calculated_MW: 28kDa/35kDa

Gen-ID 7035
UniProt P10646
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI) antibody (ABIN6568810) Western blot analysis of extracts of various cell lines, using TFPI antibody.
Image no. 2 for anti-Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI) antibody (ABIN6568810) Immunofluorescence analysis of MCF-7 cells using TFPI antibody.