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SMG7 Antikörper

SMG7 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6568670
  • Target Alle SMG7 Antikörper anzeigen
    SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))
    Reaktivität
    • 23
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 23
    Kaninchen
    Klonalität
    • 23
    Polyklonal
    Konjugat
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SMG7 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human SMG7 (NP_963863.2).
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    WB 1:200-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))
    Andere Bezeichnung
    SMG7 (SMG7 Produkte)
    Synonyme
    9430023P16Rik antikoerper, mKIAA0250 antikoerper, C1orf16 antikoerper, EST1C antikoerper, SGA56M antikoerper, Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) antikoerper, SMG7, nonsense mediated mRNA decay factor antikoerper, Smg7 antikoerper, SMG7 antikoerper
    Hintergrund
    SMG7,C1orf16,EST1C,SGA56M,This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD), a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
    Molekulargewicht

    Observed_MW: 127kDa

    Calculated_MW: 122kDa/127kDa/131kDa

    Gen-ID
    9887
    UniProt
    Q92540
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