SIM2 Antikörper

Produktnummer ABIN6568570

Produktdetails anti-SIM2 Antikörper

Target: SIM2 (Single-Minded Homolog 2 (SIM2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human SIM2 (NP_033664.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SIM2

Target: SIM2 (Single-Minded Homolog 2 (SIM2))

Andere Bezeichnung: SIM2 (SIM2 Produkte)

Synonyme: Xsim2 antikoerper, sim2-A antikoerper, xSim antikoerper, HMC13F06 antikoerper, HMC29C01 antikoerper, SIM antikoerper, bHLHe15 antikoerper, single-minded family bHLH transcription factor 2 S homeolog antikoerper, single-minded family bHLH transcription factor 2 antikoerper, single-minded homolog 2 (Drosophila) antikoerper, sim2.S antikoerper, sim2 antikoerper, SIM2 antikoerper, Sim2 antikoerper

Hintergrund: This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.

Molekulargewicht:

Observed_MW: 56kDa

Calculated_MW: 63kDa/73kDa

Gen-ID: 6493

UniProt: Q14190