HERPUD1 Antikörper

Produktnummer ABIN6568270

Produktdetails anti-HERPUD1 Antikörper

Target: HERPUD1 (Homocysteine-Inducible, Endoplasmic Reticulum Stress-Inducible, Ubiquitin-Like Domain Member 1 (HERPUD1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HERPUD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human HERPUD1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu HERPUD1

Target: HERPUD1 (Homocysteine-Inducible, Endoplasmic Reticulum Stress-Inducible, Ubiquitin-Like Domain Member 1 (HERPUD1))

Andere Bezeichnung: HERPUD1 (HERPUD1 Produkte)

Synonyme: herpud1-a antikoerper, herp antikoerper, herpud1 antikoerper, mif1 antikoerper, sup antikoerper, HERPUD1 antikoerper, zgc:114134 antikoerper, HERP antikoerper, Mif1 antikoerper, SUP antikoerper, Herp antikoerper, Mifl antikoerper, Sup antikoerper, homocysteine inducible ER protein with ubiquitin like domain 1 S homeolog antikoerper, homocysteine inducible ER protein with ubiquitin like domain 1 L homeolog antikoerper, homocysteine inducible ER protein with ubiquitin like domain 1 antikoerper, homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 antikoerper, herpud1.S antikoerper, herpud1.L antikoerper, herpud1 antikoerper, HERPUD1 antikoerper, Herpud1 antikoerper

Hintergrund:

Synonyms: HERP,HERP1,HERPUD1,Homocysteine inducible endoplasmic reticulum stress inducible ubiquitin like domain member 1,Homocysteine inducible endoplasmic reticulum stress inducible ubiquitin like domain member 1 protein,Homocysteine responsive endoplasmic reticulum resident ubiquitin like domain member 1 ,Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein,KIAA0025,Methyl methanesulfonate (MMF) inducible fragment protein 1 ,Methyl methanesulfonate (MMF)-inducible fragment protein 1,MIF1,MMS inducible,SUP

Background: The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined.

Molekulargewicht:

Observed_MW: 44kDa

Calculated_MW: 26kDa/40kDa/43kDa

Gen-ID: 9709

UniProt: Q15011

Pathways: ER-Nucleus Signaling