Proteasome (Prosome, Macropain) Subunit, alpha Type, 5 (PSMA5) Antikörper Primary Antibody
-
- Target
- Reaktivität
- Human, Maus, Ratte
- Wirt
- Kaninchen
- Klonalität
- Polyklonal
- Konjugat
- Unkonjugiert
- Applikation
- Immunohistochemistry (IHC), Western Blotting (WB)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human PSMA5
- Isotyp
- IgG
-
-
- Applikationshinweise
- WB 1:500 - 1:2000 IHC 1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- Andere Bezeichnung
- PSMA5 (PSMA5 Antibody Abstract)
- Hintergrund
Synonyms: Macropain zeta chain,Multicatalytic endopeptidase complex zeta chain,Proteasome (prosome macropain) subunit alpha type 5,Proteasome alpha5 subunit,Proteasome component 5,Proteasome subunit alpha type 5,Proteasome subunit alpha type-5,Proteasome subunit zeta,Proteasome zeta chain,PSA5,PSC5 ,PSMA5,ZETA
Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene.
- Molekulargewicht
Observed_MW: 28kDa
Calculated_MW: 20kDa/26kDa
- Gen-ID
- 5686
- UniProt
- P28066
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA