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MOB1A Antikörper (N-Term)

MOBKL1B Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB19209 unconjugated
Produktnummer ABIN656811
  • Target Alle MOB1A (MOBKL1B) Antikörper anzeigen
    MOB1A (MOBKL1B) (MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))
    Bindungsspezifität
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 5-33, N-Term
    Reaktivität
    • 45
    • 30
    • 20
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 42
    • 3
    Kaninchen
    Klonalität
    • 42
    • 3
    Polyklonal
    Konjugat
    • 20
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Dieser MOB1A Antikörper ist unkonjugiert
    Applikation
    • 20
    • 15
    • 9
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Homologie
    M, Rat
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This MOBKL1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-33 amino acids from the N-terminal region of human MOBKL1B.
    Klon
    RB19209
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product MOBKL1B Primärantikörper
  • Applikationshinweise
    WB: 1:1000. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    MOBKL1B Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Haltbarkeit
    6 months
  • Target
    MOB1A (MOBKL1B) (MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))
    Andere Bezeichnung
    MOBKL1B (MOBKL1B Produkte)
    Synonyme
    mob1 antikoerper, mob4b antikoerper, MOB1A antikoerper, MOBK1B antikoerper, MOB1 antikoerper, mats1 antikoerper, mobk1b antikoerper, mobkl1b antikoerper, MOBKL1B antikoerper, wu:fv69d04 antikoerper, zgc:56189 antikoerper, C2orf6 antikoerper, MATS1 antikoerper, Mob4B antikoerper, 4022402H07Rik antikoerper, MOB4B antikoerper, Mobk1b antikoerper, Mobkl1b antikoerper, MOB kinase activator 1A L homeolog antikoerper, MOB kinase activator 1A antikoerper, MOB kinase activator 1A pseudogene antikoerper, mob1a.L antikoerper, MOB1A antikoerper, mob1a antikoerper, LOC712156 antikoerper, Mob1a antikoerper
    Hintergrund
    Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L.
    Molekulargewicht
    25080
    Gen-ID
    55233
    NCBI Accession
    NP_060691
    UniProt
    Q9H8S9
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