Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2) Antikörper

Details zu Produkt Nr. ABIN6568075
Target
Reaktivität
Human, Maus, Ratte
55
27
25
5
5
5
5
4
2
1
1
1
1
1
Wirt
Kaninchen
50
6
Klonalität
Polyklonal
Konjugat
Unkonjugiert
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC)
42
24
13
10
6
5
1
1
1
1
Optionen
Immunogen Recombinant protein of human UHRF2
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung UHRF2 (UHRF2 Antibody Abstract)
Hintergrund

Synonyms: DKFZp434B0920,DKFZp686G0837,E3 ubiquitin-protein ligase UHRF2,MGC33463,Np95 like RING finger protein,Np95-like ring finger protein,Np95/ICBP90 like RING finger protein,Np95/ICBP90-like RING finger protein,Nuclear protein 97,Nuclear zinc finger protein Np97,RING finger protein 107,RNF 107,RP11-472F14.2,Ubiquitin like containing PHD and RING finger domains protein 2,Ubiquitin-like PHD and RING finger domain-containing protein 2,Ubiquitin-like-containing PHD and RING finger domains protein 2,Uhrf2,UHRF2,URF 2

Background: This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.

Molekulargewicht

Observed_MW: Refer to figures

Calculated_MW: 56kDa/89kDa

Gen-ID 115426
UniProt Q96PU4
Applikations-hinweise IHC 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2) antibody (ABIN6568075) Immunohistochemistry of paraffin-embedded human liver cancer using UHRF2 antibody.
Image no. 2 for anti-Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2) antibody (ABIN6568075) Immunohistochemistry of paraffin-embedded human kidney cancer using UHRF2 antibody.
Image no. 3 for anti-Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2) antibody (ABIN6568075) Immunohistochemistry of paraffin-embedded rat Intestine using UHRF2 antibody.