CD177 Antikörper (CD177 Molecule)

Details for Product anti-CD177 Antibody No. ABIN6568071
Target
Reaktivität
Human
68
7
6
5
4
4
4
Wirt
Kaninchen
39
30
1
Klonalität
Polyklonal
Konjugat
Dieser CD177 Antikörper ist unkonjugiert
7
7
7
4
2
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF)
46
31
24
18
9
8
2
1
1
1
1
Optionen
Immunogen Recombinant protein of human CD177
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung CD177 (CD177 Antibody Abstract)
Hintergrund

Synonyms: CD177,CD177 antigen,CD177 Molecule,CD177,HNA-2a,HNA2A,Human neutrophil alloantigen 2a,NB1,NB1 glycoprotein,NB1 GP,Polycythemia rubra vera 1,Polycythemia rubra vera protein 1,PRV-1,PRV1

Background: This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.

Molekulargewicht

Calculated_MW: 15kDa/27kDa/46kDa

Gen-ID 57126
UniProt Q8N6Q3
Applikations-hinweise IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-CD177 Molecule (CD177) antibody (ABIN6568071) Immunofluorescence analysis of HeLa cells using CD177 antibody.