HNMT Antikörper (Histamine N-Methyltransferase) Primary Antibody
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- Target
- Reaktivität
- Human, Maus
- Wirt
- Kaninchen
- Klonalität
- Polyklonal
- Konjugat
- Dieser HNMT Antikörper ist unkonjugiert
- Applikation
- Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human HNMT
- Isotyp
- IgG
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- Applikationshinweise
- WB 1:500 - 1:2000 IHC 1:50 - 1:200 IP 1:20 - 1:50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Andere Bezeichnung
- HNMT (HNMT Antibody Abstract)
- Hintergrund
Synonyms: EC 2.1.1.8,Histamine N methyltransferase,Histamine N-methyltransferase,HMT,HNMT,HNMT S1,HNMT S2,HNMT
Background: In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
- Molekulargewicht
Observed_MW: 27kDa
Calculated_MW: 6kDa/14kDa/33kDa
- Gen-ID
- 3176
- UniProt
- P50135