SUFUH Antikörper (Suppressor of Fused Homolog (Drosophila))

Details for Product anti-SUFUH Antibody No. ABIN6567960
Target
Reaktivität
Human, Maus, Ratte
50
30
29
7
7
7
7
4
3
3
3
3
2
1
Wirt
Kaninchen
48
1
1
Klonalität
Polyklonal
Konjugat
Dieser SUFUH Antikörper ist unkonjugiert
4
4
3
3
2
2
2
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
23
13
12
9
4
3
3
2
2
1
1
Optionen
Immunogen Recombinant protein of human SUFU
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung SUFU (SUFUH Antibody Abstract)
Hintergrund

Synonyms: OTTHUMP00000020374,OTTHUMP00000020377,OTTHUMP00000020379,PRO1280,SU FU,SU(F)U,Su(fu),SUFU,SUFU negative regulator of hedgehog signaling,SUFU,SUFUH,SUFUXL,Suppressor of fused homolog (Drosophila),Suppressor of fused homolog

Background: The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.

Molekulargewicht

Observed_MW: 54kDa

Calculated_MW: 47kDa/52kDa/53kDa

Gen-ID 51684
UniProt Q9UMX1
Pathways Hedgehog Signalweg, Tube Formation, Maintenance of Protein Location
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Suppressor of Fused Homolog (Drosophila) (SUFUH) antibody (ABIN6567960) Immunofluorescence analysis of MCF-7 cells using SUFU antibody.
Image no. 2 for anti-Suppressor of Fused Homolog (Drosophila) (SUFUH) antibody (ABIN6567960) Western blot analysis of extracts of various cell lines, using SUFU antibody.