serglycin (SRGN) Antikörper

Details zu Produkt Nr. ABIN6567891
Target
Reaktivität
Human, Maus
35
9
3
2
2
2
1
Wirt
Kaninchen
36
5
Klonalität
Polyklonal
Konjugat
Unkonjugiert
5
3
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
33
18
12
9
4
4
3
3
2
2
1
1
1
Optionen
Immunogen Recombinant protein of human SRGN
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung SRGN (SRGN Antibody Abstract)
Hintergrund

Synonyms: Chondroitin sulfate proteoglycan core protein,Cytolytic granule proteoglycan core protein,FLJ12930,gp600,Hematopoetic proteoglycan core protein,Mastocytoma proteoglycan core protein,MGC9289,OTTHUMP00000019716,P.PG,PG19 core protein,Pgsg,Platelet proteoglycan core protein,platelet proteoglycan protein core,PLATELET PROTEOGLYCAN PROTEIN CORE,PPG,PPG,PRG,PRG1,PROTEOGLYCAN 1,proteoglycan 1,secretory granule,Proteoglycan 10K core protein,Proteoglycan peptide core protein,PROTEOGLYCAN PROTEIN CORE FOR MAST CELL SECRETORY GRANULE,secretory granule proteoglycan 1,Secretory granule proteoglycan core peptide,Secretory granule proteoglycan core protein,Serglycin,serglycin proteoglycan,Sgc,Srgn,SRGN

Background: This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene.

Molekulargewicht

Observed_MW: 18kDa

Calculated_MW: 17kDa

Gen-ID 5552
UniProt P10124
Pathways Maintenance of Protein Location
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-serglycin (SRGN) antibody (ABIN6567891) Immunofluorescence analysis of A549 cells using SRGN antibody.
Image no. 2 for anti-serglycin (SRGN) antibody (ABIN6567891) Western blot analysis of extracts of various cell lines, using SRGN antibody.