Glucose-6-Phosphate Isomerase (GPI) Antikörper

Details zu Produkt Nr. ABIN6567873
Target
Reaktivität
Human, Maus, Ratte
110
57
27
6
5
4
4
4
3
3
2
2
1
Wirt
Kaninchen
108
19
15
Klonalität
Polyklonal
Konjugat
Unkonjugiert
14
11
11
6
6
6
3
2
2
2
2
2
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
115
75
27
20
15
14
12
8
5
5
5
3
2
2
2
1
1
1
Optionen
Immunogen Recombinant protein of human GPI
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung GPI (GPI Antibody Abstract)
Hintergrund

Synonyms: AMF,Aurocrine motility factor,Autocrine motility factor,DKFZp686C13233,EC 5.3.1.9,G6PI,Glucose phosphate isomerase,Glucose-6-phosphate isomerase,GNPI,GPI,Gpi1,Hexose monophosphate isomerase,Hexosephosphate isomerase,Neuroleukin,NLK,Oxoisomerase,PGI,PHI,Phosphoglucose isomerase,Phosphohexomutase,Phosphohexose isomerase,Phosphosaccharomutase,SA 36,SA-36,SA36,Sperm antigen 36

Background: This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants.

Molekulargewicht

Observed_MW: 56kDa

Calculated_MW: 63kDa/64kDa

Gen-ID 2821
UniProt P06744
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Glucose-6-Phosphate Isomerase (GPI) antibody (ABIN6567873) Immunohistochemistry of paraffin-embedded rat brain using GPI antibody.
Image no. 2 for anti-Glucose-6-Phosphate Isomerase (GPI) antibody (ABIN6567873) Immunohistochemistry of paraffin-embedded rat kidney using GPI antibody.
Image no. 3 for anti-Glucose-6-Phosphate Isomerase (GPI) antibody (ABIN6567873) Western blot analysis of extracts of various cell lines, using GPI antibody.
Image no. 4 for anti-Glucose-6-Phosphate Isomerase (GPI) antibody (ABIN6567873) Immunofluorescence analysis of U2OS cells using GPI antibody.