DLD Antikörper (Dihydrolipoamide Dehydrogenase)

Details for Product anti-DLD Antibody No. ABIN6567863
Target
Reaktivität
Human, Maus
45
20
19
12
5
3
3
3
3
1
1
1
1
Wirt
Kaninchen
44
12
Klonalität
Polyklonal
Konjugat
Dieser DLD Antikörper ist unkonjugiert
5
2
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
47
27
20
16
12
10
9
5
3
3
2
1
1
1
Optionen
Immunogen Recombinant protein of human DLD
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung DLD (DLD Antibody Abstract)
Hintergrund

Synonyms: Dehydrogenase complex,E3 component,Diaphorase,Dihydrolipoamide dehydrogenase,Dihydrolipoyl dehydrogenase,Dihydrolipoyl dehydrogenase mitochondrial,dld,DLDD,DLDH,DLDH,E3,E3 branched chain aplha-keto acid,E3 component of pyruvate dehydrogenase,E3 component of pyruvate dehydrogenase complex 2 oxo glutarate complex branched chain keto acid dehydrogenase complex,GCSL,Glycine cleavage system L protein,Glycine cleavage system protein L,LAD,lipoamide dehydrogenase,Lipoamide reductase,Lipoyl dehydrogenase,mitochondrial,OTTHUMP00000206744,OTTHUMP00000206746,OTTHUMP00000206748,OTTHUMP00000206749,PHE 3,PHE3,Pyruvate dehydrogenase component E3

Background: This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants.

Molekulargewicht

Observed_MW: 54kDa

Calculated_MW: 43kDa/49kDa/54kDa

Gen-ID 1738
UniProt P09622
Pathways Ribonucleoside Biosynthetic Process, Cell RedoxHomeostasis
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Dihydrolipoamide Dehydrogenase (DLD) antibody (ABIN6567863) Immunofluorescence analysis of HeLa cells using DLD antibody.
Image no. 2 for anti-Dihydrolipoamide Dehydrogenase (DLD) antibody (ABIN6567863) Immunohistochemistry of paraffin-embedded human liver injury using DLD antibody.
Image no. 3 for anti-Dihydrolipoamide Dehydrogenase (DLD) antibody (ABIN6567863) Western blot analysis of extracts of various cell lines, using DLD antibody.
Image no. 4 for anti-Dihydrolipoamide Dehydrogenase (DLD) antibody (ABIN6567863) Immunohistochemistry of paraffin-embedded human esophageal cancer using DLD antibody.