DDX5 Antikörper (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5)

Details for Product anti-DDX5 Antibody No. ABIN6567861
Target
Reaktivität
Human, Maus, Ratte
88
58
54
7
7
6
6
6
5
3
1
1
1
Wirt
Kaninchen
70
10
8
Klonalität
Polyklonal
Konjugat
Dieser DDX5 Antikörper ist unkonjugiert
4
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
61
27
21
15
15
14
8
7
5
3
3
3
2
2
1
Optionen
Immunogen Recombinant protein of human DDX5
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung p68 RNA Helicase (DDX5 Antibody Abstract)
Hintergrund

Synonyms: ATP dependent RNA helicase DDX5,DDX 5,Ddx5,DDX5,DEAD (Asp Glu Ala Asp) box helicase 5,DEAD (Asp Glu Ala Asp) box polypeptide 5,DEAD box 5,DEAD box protein 5,DEAD/H (Asp Glu Ala Asp/His) box polypeptide 5 (RNA helicase,68kD),G17P1,HELR,HLR1,HUMP68,P68,p68 RNA helicase,Probable ATP dependent RNA helicase DDX5,Probable ATP-dependent RNA helicase DDX5,RNA helicase p68

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a RNA-dependent ATPase, and also a proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen. Alternative splicing results in multiple transcript variants.

Molekulargewicht

Observed_MW: 69kDa

Calculated_MW: 60kDa/69kDa

Gen-ID 1655
UniProt P17844
Pathways Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Response to DNA Damage Stimulus
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5) antibody (ABIN6567861) Immunohistochemistry of paraffin-embedded mouse liver using DDX5 antibody.
Image no. 2 for anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5) antibody (ABIN6567861) Immunohistochemistry of paraffin-embedded rat lung using DDX5 antibody.
Image no. 3 for anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5) antibody (ABIN6567861) Immunofluorescence analysis of HeLa cells using DDX5 antibody.
Image no. 4 for anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5) antibody (ABIN6567861) Western blot analysis of extracts of various cell lines, using DDX5 antibody.
Image no. 5 for anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5) antibody (ABIN6567861) Immunohistochemistry of paraffin-embedded human lung cancer using DDX5 antibody.