F11R Antikörper (F11 Receptor)

Details for Product anti-F11R Antibody No. ABIN6567453
Target
Reaktivität
Human, Maus, Ratte
88
57
42
5
3
3
2
2
2
1
1
1
Wirt
Kaninchen
60
22
18
7
2
Klonalität
Polyklonal
Konjugat
Dieser F11R Antikörper ist unkonjugiert
10
10
4
4
4
3
3
3
3
3
3
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
58
38
22
17
16
13
13
11
10
3
3
2
2
1
1
1
1
1
Optionen
Immunogen Recombinant protein of human F11R
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung JAM-A (F11R Antibody Abstract)
Hintergrund

Synonyms: CD 321,CD321,CD321 antigen,ESTM33,F11 receptor,F11R,JAM 1,JAM A,JAM,JAM-1,JAM-A,JAM1,JAM1,JAMA,JCAM,Jcam1,Junction adhesion molecule 1,Junction adhesion molecule,mouse,homolog of,Junctional adhesion molecule 1,Junctional adhesion molecule A,KAT,Ly106,PAM 1,PAM-1,PAM1,Platelet adhesion molecule 1,Platelet adhesion molecule,Platelet F11 receptor,PRO301,UNQ264

Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

Molekulargewicht

Observed_MW: 40kDa

Calculated_MW: 27kDa/32kDa

Gen-ID 50848
UniProt Q9Y624
Pathways Cell-Cell Junction Organization
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-F11 Receptor (F11R) antibody (ABIN6567453) Immunofluorescence analysis of HeLa cells using F11R antibody.
Image no. 2 for anti-F11 Receptor (F11R) antibody (ABIN6567453) Western blot analysis of extracts of various cell lines, using F11R antibody.