Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) Antikörper

Details zu Produkt Nr. ABIN6567302
Target
Reaktivität
Human, Maus
81
33
23
2
2
2
2
2
2
1
1
1
1
Wirt
Kaninchen
58
17
7
Klonalität
Polyklonal
Konjugat
Unkonjugiert
6
5
5
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
54
33
17
13
10
7
6
6
2
2
1
1
Optionen
Immunogen Recombinant protein of human RASSF1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung RASSF1 (RASSF1 Antibody Abstract)
Hintergrund

Synonyms: Ras association domain containing protein 1,Ras association domain family 1,Ras association domain family protein 1,Ras association domain-containing protein 1,RASF1,RASSF 1a,Rassf1,RASSF1A,RASSF1A isoform,Tumor suppressor protein RDA32

Background: This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Molekulargewicht

Observed_MW: 39kDa

Calculated_MW: 8kDa/9kDa/16kDa/21kDa/31kDa/38kDa/39kDa

Gen-ID 11186
UniProt Q9NS23
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) antibody (ABIN6567302) Immunofluorescence analysis of HeLa cells using RASSF1 antibody.
Image no. 2 for anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) antibody (ABIN6567302) Western blot analysis of extracts of various cell lines, using RASSF1 antibody.