PDGFB Antikörper
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- Target Alle PDGFB Antikörper anzeigen
- PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PDGFB Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human PDGFB (NP_002599.1).
- Isotyp
- IgG
- Top Product
- Discover our top product PDGFB Primärantikörper
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- Applikationshinweise
- IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))
- Andere Bezeichnung
- PDGFB (PDGFB Produkte)
- Synonyme
- PDGF-2 antikoerper, PDGF2 antikoerper, SIS antikoerper, SSV antikoerper, c-sis antikoerper, pdgf2 antikoerper, sis antikoerper, si:ch211-79m20.1 antikoerper, si:dkey-261d11.1 antikoerper, PDGF-B antikoerper, Sis antikoerper, platelet derived growth factor subunit B antikoerper, platelet-derived growth factor beta polypeptide antikoerper, platelet derived growth factor subunit B S homeolog antikoerper, platelet-derived growth factor beta polypeptide a antikoerper, platelet derived growth factor, B polypeptide antikoerper, PDGFB antikoerper, pdgfb.S antikoerper, pdgfba antikoerper, Pdgfb antikoerper
- Hintergrund
- This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing results in multiple transcript variants.
- Molekulargewicht
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Observed_MW: 27kDa
Calculated_MW: 25kDa/27kDa
- Gen-ID
- 5155
- UniProt
- P01127
- Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Carbohydrate Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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