Metabotropic Glutamate Receptor 1 Antikörper

Produktnummer ABIN6567063

Produktdetails anti-Metabotropic Glutamate Receptor 1 Antikörper

Target: Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Metabotropic Glutamate Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human GRM1 (NP_001264993.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Metabotropic Glutamate Receptor 1

Target: Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

Andere Bezeichnung: GRM1 (GRM1 Produkte)

Synonyme: fj39d05 antikoerper, wu:fj39d05 antikoerper, si:ch211-51a19.1 antikoerper, Glura antikoerper, mGlutR antikoerper, GB18621 antikoerper, GPRC1A antikoerper, MGLU1 antikoerper, MGLUR1 antikoerper, SCAR13 antikoerper, 4930455H15Rik antikoerper, ENSMUSG00000075319 antikoerper, Gm10828 antikoerper, Gprc1a antikoerper, mGluR1 antikoerper, nmf373 antikoerper, rcw antikoerper, wobl antikoerper, glutamate metabotropic receptor 1 antikoerper, glutamate receptor, metabotropic 1a antikoerper, metabotropic glutamate receptor 1 antikoerper, glutamate receptor, metabotropic 1 antikoerper, GRM1 antikoerper, grm1a antikoerper, mGlutR1 antikoerper, Grm1 antikoerper

Hintergrund: This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht:

Observed_MW: 132kDa

Calculated_MW: 101kDa/132kDa

Gen-ID: 2911

UniProt: Q13255