KREMEN1 Antikörper (Kringle Containing Transmembrane Protein 1) Primary Antibody
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- Target
- Reaktivität
- Human, Maus, Ratte
- Wirt
- Kaninchen
- Klonalität
- Polyklonal
- Konjugat
- Dieser KREMEN1 Antikörper ist unkonjugiert
- Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human KREMEN1
- Isotyp
- IgG
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- Applikationshinweise
- WB 1:500 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Andere Bezeichnung
- KREMEN1 (KREMEN1 Antibody Abstract)
- Hintergrund
Synonyms: AV002070,Dickkopf receptor,KREM1,KREMEN,Kremen protein 1,Kremen protein 1 precursor,Kremen1,Kringle coding gene marking the eye and the nose,Kringle containing protein marking the eye and the nose,Kringle containing transmembrane protein 1,Kringle containing transmembrane protein,Kringle domain containing transmembrane protein 1,Kringle domain-containing transmembrane protein 1,Kringle-containing protein marking the eye and the nose,KRM1,RP23 293J16.1
Background: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
- Molekulargewicht
Observed_MW: 70kDa
Calculated_MW: 50kDa/51kDa/53kDa
- Gen-ID
- 83999
- UniProt
- Q96MU8
- Pathways
- WNT Signalweg