CEBPA Antikörper

Produktnummer ABIN6566689

Produktdetails anti-CEBPA Antikörper

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEBPA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human CEBPA (NP_004355.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CEBPA

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Andere Bezeichnung: CEBPA (CEBPA Produkte)

Synonyme: C/EBP-alpha antikoerper, CEBP antikoerper, C/ebpalpha antikoerper, CBF-A antikoerper, Cebp antikoerper, DBPCEP antikoerper, c/ebpa antikoerper, cb1062 antikoerper, wu:fj20f03 antikoerper, C/EBP antikoerper, C/EBPalpha antikoerper, xC/EBP antikoerper, cC/EBP antikoerper, C/EBP alpha antikoerper, CCAAT/enhancer binding protein alpha antikoerper, CCAAT/enhancer binding protein (C/EBP), alpha antikoerper, CCAAT/enhancer binding protein alpha L homeolog antikoerper, CEBPA antikoerper, Cebpa antikoerper, cebpa antikoerper, cebpa.L antikoerper

Hintergrund: This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.

Molekulargewicht:

Observed_MW: 38kDa

Calculated_MW: 25kDa/35kDa/37kDa/41kDa

Gen-ID: 1050

UniProt: P49715

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation