X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) Antikörper

Details zu Produkt Nr. ABIN6566685
Target
Reaktivität
Human, Affe, Maus, Ratte
225
80
58
16
4
3
2
2
2
1
1
1
1
1
Wirt
Kaninchen
185
36
7
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
17
10
10
10
8
7
7
6
6
6
6
6
2
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
181
118
96
69
64
45
31
18
13
4
3
3
2
1
1
1
1
1
Optionen
Immunogen A synthetic peptide of human XRCC6
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung XRCC6 (XRCC6 Antibody Abstract)
Hintergrund

Synonyms: 5''-deoxyribose-5-phosphate lyase Ku70,5''-dRP lyase Ku70,70 kDa subunit of Ku antigen,ATP dependent DNA helicase 2 subunit 1,ATP dependent DNA helicase II 70 kDa subunit,ATP-dependent DNA helicase 2 subunit 1,ATP-dependent DNA helicase II 70 kDa subunit,CTC box binding factor 75 kDa subunit,CTC box-binding factor 75 kDa subunit,CTC75,CTCBF,DNA repair protein XRCC6,G22P1,Ku 70,Ku autoantigen p70 subunit,Ku autoantigen,70  kDa,Ku p70,Ku70,Ku70 DNA binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa,Kup70,Lupus Ku autoantigen protein p70,ML8,Thyroid autoantigen 70kD (Ku antigen),Thyroid autoantigen,Thyroid lupus autoantigen,Thyroid lupus autoantigen p70,Thyroid-lupus autoantigen,TLAA,X ray repair complementing defective repair in Chinese hamster cells 6,X-ray repair complementing defective repair in Chinese hamster cells 6,X-ray repair cross-complementing protein 6,XRCC 6,Xrcc6,XRCC6

Background: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Molekulargewicht

Observed_MW: 70kDa

Calculated_MW: 65kDa/69kDa

Gen-ID 2547
UniProt P12956
Pathways DNA Reparatur
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) antibody (ABIN6566685) Immunohistochemistry of paraffin-embedded human brain astrocytoma using XRCC6 Antibody.
Image no. 2 for anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) antibody (ABIN6566685) Immunohistochemistry of paraffin-embedded human leiomyoma of uterus using XRCC6 Antib...
Image no. 3 for anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) antibody (ABIN6566685) Immunohistochemistry of paraffin-embedded human breast using XRCC6 Antibody.
Image no. 4 for anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) antibody (ABIN6566685) Immunofluorescence analysis of HeLa cells using XRCC6 antibody.
Image no. 5 for anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) antibody (ABIN6566685) Western blot analysis of extracts of various cell lines, using XRCC6 antibody.