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FGFR3 Antikörper

FGFR3 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6566588
  • Target Alle FGFR3 Antikörper anzeigen
    FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
    Reaktivität
    • 118
    • 50
    • 42
    • 4
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 111
    • 7
    • 1
    Kaninchen
    Klonalität
    • 98
    • 21
    Polyklonal
    Konjugat
    • 42
    • 13
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser FGFR3 Antikörper ist unkonjugiert
    Applikation
    • 89
    • 48
    • 47
    • 13
    • 13
    • 10
    • 10
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human FGFR3
    Isotyp
    IgG
    Top Product
    Discover our top product FGFR3 Primärantikörper
  • Applikationshinweise
    WB 1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
    Andere Bezeichnung
    FGFR3 (FGFR3 Produkte)
    Synonyme
    FGFR3 antikoerper, LOC100034114 antikoerper, ACH antikoerper, CD333 antikoerper, CEK2 antikoerper, HSFGFR3EX antikoerper, JTK4 antikoerper, FR3 antikoerper, Fgfr-3 antikoerper, Flg-2 antikoerper, HBGFR antikoerper, Mfr3 antikoerper, sam3 antikoerper, fc27h01 antikoerper, wu:fc27h01 antikoerper, fibroblast growth factor receptor 3 antikoerper, fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog antikoerper, FGFR3 antikoerper, fgfr3.S antikoerper, Fgfr3 antikoerper, fgfr3 antikoerper
    Hintergrund

    Synonyms: ACH,CD 333,CD333,CD333 antigen,CEK 2,CEK2,FGFR 3,FGFR-3,FGFR3,FGFR3,Fibroblast growth factor receptor 3 (achondroplasia thanatophoric dwarfism),Fibroblast growth factor receptor 3,Heparin binding growth factor receptor,HSFGFR3EX,Hydroxyaryl protein kinase,JTK 4,JTK4,MFR 3,SAM 3,Tyrosine kinase JTK 4,Tyrosine kinase JTK4,Z FGFR 3

    Background: This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described.

    Molekulargewicht

    Observed_MW: 115kDa

    Calculated_MW: 75kDa/85kDa/87kDa/88kDa

    Gen-ID
    2261
    UniProt
    P22607
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Growth Factor Binding
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