CREB2 Antikörper

Details zu Produkt Nr. ABIN6566494
Target
Reaktivität
Human, Maus, Ratte
Wirt
Kaninchen
Klonalität
Polyklonal
Applikation
Western Blotting (WB)
Optionen
Immunogen Recombinant protein of human ATF4
Isotyp IgG
Reinigung Affinity purification
Target
Hintergrund

Synonyms: Activating transcription factor 4,ATF 4,ATF4,ATF4 protein,ATF4,cAMP-dependent transcription factor ATF-4,cAMP-responsive element-binding protein 2,CREB 2,CREB-2,CREB2,Cyclic AMP dependent transcription factor ATF 4,Cyclic AMP response element binding protein 2,Cyclic AMP-dependent transcription factor ATF-4,Cyclic AMP-responsive element-binding protein 2,DNA binding protein TAXREB67,DNA-binding protein TAXREB67,Tax Responsive Enhancer Element B67,Tax-responsive enhancer element-binding protein 67,TaxREB67,TXREB

Background: This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.

Molekulargewicht

Observed_MW: 37kDa

Calculated_MW: 38kDa

Gen-ID 468
UniProt P18848
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-CREB2 antibody (ABIN6566494) Western blot analysis of extracts of various cell lines, using ATF4 Antibody.
Produkt verwendet in: Anasa, Manickam, Talwar, Ravanan: "Identification of ASB7 as ER stress responsive gene through a genome wide in silico screening for genes with ERSE." in: PLoS ONE, Vol. 13, Issue 4, pp. e0194310, 2018 (PubMed).