Calpastatin Antikörper (CAST)

Details for Product anti-CAST Antibody No. ABIN6566472
Target
Reaktivität
Human, Maus, Ratte
62
20
18
2
Wirt
Kaninchen
47
15
3
Klonalität
Polyklonal
Konjugat
Dieser Calpastatin Antikörper ist unkonjugiert
5
4
4
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
39
26
17
16
13
12
6
4
2
2
2
1
1
Optionen
Immunogen A synthetic peptide of human CAST
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung CAST (CAST Antibody Abstract)
Hintergrund

Synonyms: BS 17,Calpain inhibitor,Calpastatin,Cast,Heart type calpastatin,ICAL,MGC9402,Sperm BS 17 component,Sperm BS-17 component

Background: The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

Molekulargewicht

Observed_MW: 124kDa

Calculated_MW: 63kDa/71- 84kDa

Gen-ID 831
UniProt P20810
Applikations-hinweise WB 1:200 - 1:2000 IHC 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Calpastatin (CAST) antibody (ABIN6566472) Immunohistochemistry of paraffin-embedded rat heart using CAST antibody.
Image no. 2 for anti-Calpastatin (CAST) antibody (ABIN6566472) Immunohistochemistry of paraffin-embedded human stomach using CAST antibody.
Image no. 3 for anti-Calpastatin (CAST) antibody (ABIN6566472) Western blot analysis of extracts of H460 cells, using CAST antibody.
Image no. 4 for anti-Calpastatin (CAST) antibody (ABIN6566472) Immunohistochemistry of paraffin-embedded mouse brain using CAST antibody.