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Calpain 6 Antikörper (AA 390-419)

CAPN6 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB19561 unconjugated
Produktnummer ABIN656477
  • Target Alle Calpain 6 (CAPN6) Antikörper anzeigen
    Calpain 6 (CAPN6)
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    AA 390-419
    Reaktivität
    • 31
    • 6
    • 3
    Human
    Wirt
    • 29
    • 3
    Kaninchen
    Klonalität
    • 29
    • 3
    Polyklonal
    Konjugat
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Calpain 6 Antikörper ist unkonjugiert
    Applikation
    • 22
    • 20
    • 17
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CAPN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 390-419 amino acids from the Central region of human CAPN6.
    Klon
    RB19561
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product CAPN6 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    CAPN6 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Haltbarkeit
    6 months
  • Target
    Calpain 6 (CAPN6)
    Andere Bezeichnung
    CAPN6 (CAPN6 Produkte)
    Synonyme
    CAPN6 antikoerper, CANPX antikoerper, CAPNX antikoerper, CalpM antikoerper, DJ914P14.1 antikoerper, calpain 6 antikoerper, CAPN6 antikoerper, Capn6 antikoerper
    Hintergrund
    Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.
    Molekulargewicht
    74576
    Gen-ID
    827
    NCBI Accession
    NP_055104
    UniProt
    Q9Y6Q1
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