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Kaninchen anti-Maus IgA Antikörper (Cy5.5)

WB, IF (p) Polyclonal IgG Cy5.5
Produktnummer ABIN673046
  • Target Alle IgA Produkte
    IgA
    Reaktivität
    • 160
    • 57
    • 44
    • 16
    • 16
    • 14
    • 14
    • 13
    • 13
    • 12
    • 10
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Maus
    Wirt
    • 201
    • 97
    • 49
    • 17
    • 12
    • 6
    • 2
    Kaninchen
    Klonalität
    • 307
    • 62
    Polyklonal
    Konjugat
    • 87
    • 52
    • 49
    • 38
    • 28
    • 26
    • 8
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cy5.5
    Applikation
    • 181
    • 135
    • 130
    • 111
    • 100
    • 96
    • 56
    • 40
    • 38
    • 29
    • 28
    • 24
    • 22
    • 18
    • 17
    • 17
    • 17
    • 7
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus
    Aufreinigung
    affinity Purified by Protein A.
    Immunogen
    Mouse IgA protein purified from serum
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:500-2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Protect conjugated products from light.
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    IgA
    Abstract
    IgA Produkte
    Substanzklasse
    Antibody
    Hintergrund
    Optional[synonyms]: Mouse IgA (immunoglobulin A) is a glycosylated protein of 160 kDa and is produced as a monomer or as a J chain-linked dimer. Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces such as saliva, gastrointestinal secretion, bronchial fluids, and milk. Mucosal IgA plays a major role in host defense by neutralizing infectious agents at mucosal surfaces. The production is usually local and antigen-specific IgA-producing B cells can be found in regions under the lamina propria where they mature into dimeric IgA-producing plasma cells. IgA deficiency is the most common immunodeficiency that may affect both serum and mucosal-produced IgA. OR: The secretory component is a component of immunoglobulin A (IgA) which consists of a portion of the polymeric immunoglobulin receptor. Polymeric IgA binds to the polymeric immunoglobulin receptor on the basolateral surface of epithelial cells and is taken up into the cell via transcytosis. The receptor-IgA complex passes through the cellular compartments before being secreted on the luminal surface of the epithelial cells, still attached to the receptor. Proteolysis of the receptor occurs and the dimeric IgA molecule, along with the secretory component, are free to diffuse throughout the lumen.

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