CD133 Antikörper (Prominin 1)

Details for Product anti-PROM1 Antibody No. ABIN6559814
Target
Reaktivität
Human
4
Wirt
Maus
4
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser CD133 Antikörper ist unkonjugiert
2
1
Applikation
Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB)
4
4
3
1
Optionen
Immunogen WERI-RB-1 retinoblastoma cell line
Klon W6B3C1
Isotyp IgG1
Spezifität The mouse monoclonal antibody W6B3C1 recognizes a glycosylated epitope 1 on human CD133 (CD133/1), a 120 kDa glycoprotein of prominin family, expressed e.g. on progenitor cells. This antibody is important for identification of stem cells and tumor cells.
HLDA VII Workshop
Kreuzreaktivität (Details) Human
Reinigung Purified from hybridoma culture supernatant by protein-A affinity chromatography.
Reinheit > 95 % (by SDS-PAGE)
Target
Andere Bezeichnung CD133 (PROM1 Antibody Abstract)
Hintergrund CD133 (prominin 1) is a 5-transmembrane glycoprotein with extracellular N- and intracellular C-terminus. CD133 function remains to be elucidated, but it can be used as a cancer stem cell marker. Its expression pattern in progenitor cells is similar to CD34, i.e. on hematopoietic stem cells in bone marrow, cord blood, neural stem cells, retinoblastoma, or endothelial precursor cells (not mature endothelial cells). It is being used for identification and isolation of hematopoietic stem cells, including isolation for stem cell transplantation. Expression of CD133 correlates with differentiation of human colon cancer cells.
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Bilder
Image no. 1 for anti-Prominin 1 (PROM1) antibody (ABIN6559814) Surface staining of CD133 in human peripheral blood with anti-CD133 (W6B3C1) purified...