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STARD6 Antikörper (C-Term)

STARD6 Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB29820 unconjugated
Produktnummer ABIN655777
  • Target Alle STARD6 Antikörper anzeigen
    STARD6 (StAR-Related Lipid Transfer (START) Domain Containing 6 (STARD6))
    Bindungsspezifität
    • 7
    • 7
    • 7
    • 1
    AA 187-215, C-Term
    Reaktivität
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 15
    Kaninchen
    Klonalität
    • 15
    Polyklonal
    Konjugat
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser STARD6 Antikörper ist unkonjugiert
    Applikation
    • 15
    • 12
    • 12
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This STARD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-215 amino acids from the C-terminal region of human STARD6.
    Klon
    RB29820
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • LaVoie, Whitfield, Shi, King, Bose, Hui: "STARD6 is expressed in steroidogenic cells of the ovary and can enhance de novo steroidogenesis." in: Experimental biology and medicine (Maywood, N.J.), Vol. 239, Issue 4, pp. 430-5, (2014) (PubMed).

  • Target
    STARD6 (StAR-Related Lipid Transfer (START) Domain Containing 6 (STARD6))
    Andere Bezeichnung
    STARD6 (STARD6 Produkte)
    Synonyme
    1700011K09Rik antikoerper, 4833424I06Rik antikoerper, 4933429L05Rik antikoerper, AI644424 antikoerper, StAR related lipid transfer domain containing 6 antikoerper, StAR-related lipid transfer (START) domain containing 6 antikoerper, STARD6 antikoerper, Stard6 antikoerper
    Hintergrund
    Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1, MIM 184756) and by liver X receptors (e.g., LXRA, MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR, MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD6 (Soccio et al., 2002 [PubMed 12011452]).
    Gen-ID
    147323
    NCBI Accession
    NP_631910
    UniProt
    P59095
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