CYP11B2 Antikörper (AA 120-147)

Produktnummer ABIN655163

Produktdetails anti-CYP11B2 Antikörper

Target: CYP11B2 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))

Bindungsspezifität: AA 120-147

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP11B2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CYP11B2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-147 amino acids from the Central region of human CYP11B2.

Klon: RB16930

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. IHC-P: 1:10~50. IHC-P: 1:25. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu CYP11B2

Target: CYP11B2 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))

Andere Bezeichnung: CYP11B2 (CYP11B2 Produkte)

Synonyme: ALDOS antikoerper, CPN2 antikoerper, CYP11B antikoerper, CYP11BL antikoerper, CYPXIB2 antikoerper, P-450C18 antikoerper, P450C18 antikoerper, P450aldo antikoerper, Cpn2 antikoerper, Cyp11b antikoerper, Cyp11b-2 antikoerper, Cp45as antikoerper, Cyp11b3 antikoerper, RNCP45AS antikoerper, cytochrome P450 family 11 subfamily B member 2 antikoerper, cytochrome P450, family 11, subfamily b, polypeptide 2 antikoerper, aldosterone synthase antikoerper, cytochrome P450, family 11, subfamily B, polypeptide 2 antikoerper, cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2 antikoerper, CYP11B2 antikoerper, Cyp11b2 antikoerper

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.

Molekulargewicht: 57560

Gen-ID: 1585

NCBI Accession: NP_000489

UniProt: P19099

Pathways: ACE Inhibitor Pathway, Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Feeding Behaviour