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NAMPT Antikörper (AA 400-426)

NAMPT Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB22920 unconjugated
Produktnummer ABIN652958
  • Target Alle NAMPT Antikörper anzeigen
    NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))
    Bindungsspezifität
    • 18
    • 15
    • 15
    • 13
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 400-426
    Reaktivität
    • 139
    • 53
    • 51
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 147
    • 10
    • 3
    • 1
    • 1
    Kaninchen
    Klonalität
    • 149
    • 14
    Polyklonal
    Konjugat
    • 67
    • 24
    • 13
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser NAMPT Antikörper ist unkonjugiert
    Applikation
    • 86
    • 66
    • 45
    • 26
    • 26
    • 20
    • 20
    • 18
    • 14
    • 12
    • 8
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M, Pig, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This NAMPT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-426 amino acids from the Central region of human NAMPT.
    Klon
    RB22920
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product NAMPT Primärantikörper
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Zhang, Tong, Huang: "Nicotinamide phosphoribosyl transferase (Nampt) is a target of microRNA-26b in colorectal cancer cells." in: PLoS ONE, Vol. 8, Issue 7, pp. e69963, (2013) (PubMed).

    Pittelli, Formentini, Faraco, Lapucci, Rapizzi, Cialdai, Romano, Moneti, Moroni, Chiarugi: "Inhibition of nicotinamide phosphoribosyltransferase: cellular bioenergetics reveals a mitochondrial insensitive NAD pool." in: The Journal of biological chemistry, Vol. 285, Issue 44, pp. 34106-14, (2010) (PubMed).

  • Target
    NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))
    Andere Bezeichnung
    NAMPT (NAMPT Produkte)
    Synonyme
    1110035O14Rik antikoerper, PBEF antikoerper, PBEF1 antikoerper, VF antikoerper, VISFATIN antikoerper, AI314458 antikoerper, AI480535 antikoerper, NAmPRTase antikoerper, Pbef antikoerper, Pbef1 antikoerper, Visfatin antikoerper, visfatin antikoerper, pbef antikoerper, pbef1 antikoerper, nicotinamide phosphoribosyltransferase antikoerper, Nicotinamide phosphoribosyltransferase antikoerper, nicotinamide phosphoribosyltransferase S homeolog antikoerper, NAMPT antikoerper, Nampt antikoerper, nampt antikoerper, Smon_0680 antikoerper, Mrub_2845 antikoerper, Cseg_3704 antikoerper, BC1002_3997 antikoerper, Ftrac_2686 antikoerper, Varpa_5681 antikoerper, Celal_3900 antikoerper, Deima_0880 antikoerper, BC1001_3724 antikoerper, Celly_1696 antikoerper, Clole_1542 antikoerper, Tsp_05934 antikoerper, nampt.S antikoerper
    Hintergrund
    NAMPT catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
    Molekulargewicht
    55521
    Gen-ID
    10135
    NCBI Accession
    NP_005737
    UniProt
    P43490
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