PRELP Antikörper (AA 119-148)

Produktnummer ABIN652218

Produktdetails anti-PRELP Antikörper

Target: PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

Bindungsspezifität: AA 119-148

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRELP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PRELP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the Central region of human PRELP.

Klon: RB18590

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PRELP

Target: PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

Andere Bezeichnung: PRELP (PRELP Produkte)

Synonyme: 7330409J17Rik antikoerper, SLRR2A antikoerper, MST161 antikoerper, MSTP161 antikoerper, proline arginine-rich end leucine-rich repeat antikoerper, proline and arginine rich end leucine rich repeat protein antikoerper, Prelp antikoerper, PRELP antikoerper

Hintergrund: PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.

Molekulargewicht: 43810

Gen-ID: 5549

NCBI Accession: NP_002716, NP_958505

UniProt: P51888

Pathways: Glycosaminoglycan Metabolic Process