VLDLR Antikörper (Very Low Density Lipoprotein Receptor) (AA 484-510)

Details for Product anti-VLDLR Antibody No. ABIN651940, Anbieter: Anmelden zum Anzeigen
Antigen
  • CARMQ1
  • CHRMQ1
  • VLDLRCH
  • AA408956
  • AI451093
  • AW047288
  • very low density lipoprotein receptor
  • MAM and LDL receptor class A domain containing 1
  • VLDLR
  • Vldlr
  • MALRD1
Epitop
AA 484-510, Center
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16
8
7
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7
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3
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1
1
Reaktivität
Human
133
68
39
19
Wirt
Kaninchen
83
47
Klonalität (Klon)
Polyklonal ()
Konjugat
Dieser VLDLR Antikörper ist unkonjugiert
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7
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2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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58
52
47
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37
13
3
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1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen This VLDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-510 AA from the Central region of human VLDLR.
Klon RB21297
Isotyp Ig Fraction
Spezifität This VLDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 491-518 amino acids from the Central region of human VLDLR.
Homologie Rabbit
Reinigung This antibody is purified through a protein A column, followed by peptide affinity purification.
Andere Bezeichnung VLDLR (VLDLR Antibody Abstract)
Hintergrund The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene. [provided by RefSeq].
Synonyms: Very low-density lipoprotein receptor,VLDLR,
Molekulargewicht 96098 DA
Gen-ID 7436
NCBI Accession NP_003374
UniProt P98155
Forschungsgebiet Cell Signaling, Protein Modifications, Cell Structure, Metabolism
Pathways Cellular Response to Molecule of Bacterial Origin
Applikationshinweise WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit 6 months
Bilder des Herstellers
Western Blotting (WB) image for anti-Very Low Density Lipoprotein Receptor (VLDLR) (AA 484-510), (Center) antibody (ABIN651940) VLDLR Antibody (Center) (ABIN651940) western blot analysis in 293 cell line lysates (...
Immunohistochemistry (IHC) image for anti-Very Low Density Lipoprotein Receptor (VLDLR) (AA 484-510), (Center) antibody (ABIN651940) VLDLR Antibody (Center) (ABIN651940) immunohistochemistry analysis in formalin fixed ...
Flow Cytometry (FACS) image for anti-Very Low Density Lipoprotein Receptor (VLDLR) (AA 484-510), (Center) antibody (ABIN651940) VLDLR Antibody (Center) (ABIN651940) flow cytometric analysis of 293 cells (right his...
Allgemeine Veröffentlichungen Sakai, Tiebel, Ljungberg, Sullivan, Lee, Terashima, Li, Kobayashi, Lu, Chan, Oka: "A neuronal VLDLR variant lacking the third complement-type repeat exhibits high capacity binding of apoE containing lipoproteins." in: Brain research, Vol. 1276, pp. 11-21, 2009 (PubMed).

Francis, Hamon, Ott, Weleber, Klein: "Polymorphisms in C2, CFB and C3 are associated with progression to advanced age related macular degeneration associated with visual loss." in: Journal of medical genetics, Vol. 46, Issue 5, pp. 300-7, 2009 (PubMed).

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