XRCC1 Antikörper (AA 407-435)

Produktnummer ABIN651735

Produktdetails anti-XRCC1 Antikörper

Target: XRCC1 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1))

Bindungsspezifität: AA 407-435

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XRCC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This XRCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-435 amino acids from the Central region of human XRCC1.

Klon: RB24559

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:25. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu XRCC1

Target: XRCC1 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1))

Andere Bezeichnung: XRCC1 (XRCC1 Produkte)

Synonyme: xrcc1 antikoerper, MGC80909 antikoerper, XRCC1 antikoerper, rcc antikoerper, RCC antikoerper, Xrcc-1 antikoerper, X-ray repair complementing defective repair in Chinese hamster cells 1 antikoerper, X-ray repair cross complementing 1 antikoerper, xrcc1 antikoerper, XRCC1 antikoerper, Xrcc1 antikoerper

Hintergrund: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Molekulargewicht: 69477

Gen-ID: 7515

NCBI Accession: NP_006288

UniProt: P18887

Pathways: DNA Reparatur