GNB1 Antikörper (N-Term)

Produktnummer ABIN651226

Produktdetails anti-GNB1 Antikörper

Target: GNB1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1 (GNB1))

Bindungsspezifität: AA 1-30, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Homologie: B, Ha, Zf, M, Rat, X

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GNB1.

Klon: RB26119

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-GNB1 Antikörper (ABIN651226)

Liu, Qin, Yu, Soares, Yang, Weng, Li, Gao, Lu, Hu, Liu, Jiang, Liu, Shu, Tang, Liu: "Pathogenic mutations in retinitis pigmentosa 2 predominantly result in loss of RP2 protein stability in humans and zebrafish." in: The Journal of biological chemistry, Vol. 292, Issue 15, pp. 6225-6239, (2017) (PubMed).

Liu, Chen, Yu, Raghupathy, Liu, Qin, Li, Huang, Liao, Wang, Zou, Shu, Tang, Liu: "Knockout of RP2 decreases GRK1 and rod transducin subunits and leads to photoreceptor degeneration in zebrafish." in: Human molecular genetics, Vol. 24, Issue 16, pp. 4648-59, (2015) (PubMed).

Details zu GNB1

Target: GNB1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1 (GNB1))

Andere Bezeichnung: GNB1 (GNB1 Produkte)

Synonyme: gnb1 antikoerper, wu:fb50b09 antikoerper, wu:fj94h04 antikoerper, AA409223 antikoerper, C77571 antikoerper, Gnb-1 antikoerper, XGB1 antikoerper, xgbeta1 antikoerper, GNB1x antikoerper, fb39f01 antikoerper, gnb1l antikoerper, wu:fb39f01 antikoerper, wu:fb98e06 antikoerper, wu:fj09d12 antikoerper, zgc:55774 antikoerper, G protein subunit beta 1 antikoerper, guanine nucleotide binding protein (G protein), beta polypeptide 1a antikoerper, guanine nucleotide binding protein (G protein), beta 1 antikoerper, guanine nucleotide binding protein (G protein), beta polypeptide 1 S homeolog antikoerper, guanine nucleotide binding protein (G protein), beta polypeptide 1b antikoerper, GNB1 antikoerper, gnb1a antikoerper, Gnb1 antikoerper, gnb1.S antikoerper, gnb1b antikoerper

Hintergrund: GNB1 integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This protein uses alternative polyadenylation signals.

Molekulargewicht: 37377

Gen-ID: 2782

NCBI Accession: NP_002065

UniProt: P62873

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interaktom