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KCNQ2 Antikörper (N-Term)

KCNQ2 Reaktivität: Ratte, Human, Maus, Hund WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN633754
  • Target Alle KCNQ2 Antikörper anzeigen
    KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))
    Bindungsspezifität
    • 16
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 31
    • 20
    • 15
    • 12
    • 11
    • 7
    • 7
    • 5
    • 5
    • 5
    • 2
    • 2
    Ratte, Human, Maus, Hund
    Wirt
    • 35
    • 1
    Kaninchen
    Klonalität
    • 36
    Polyklonal
    Konjugat
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KCNQ2 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 16
    • 13
    • 13
    • 8
    • 8
    • 7
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB)
    Spezifität
    KCNQ2 antibody was raised against the N terminal of KCNQ2
    Aufreinigung
    Affinity purified
    Immunogen
    KCNQ2 antibody was raised using the N terminal of KCNQ2 corresponding to a region with amino acids YRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFL
    Top Product
    Discover our top product KCNQ2 Primärantikörper
  • Applikationshinweise
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    Kommentare

    KCNQ2 Blocking Peptide, catalog no. 33R-10224, is also available for use as a blocking control in assays to test for specificity of this KCNQ2 antibody

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of KCNQ2 antibody in PBS
    Konzentration
    Lot specific
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))
    Andere Bezeichnung
    KCNQ2 (KCNQ2 Produkte)
    Synonyme
    BFNC antikoerper, BFNS1 antikoerper, EBN antikoerper, EBN1 antikoerper, EIEE7 antikoerper, ENB1 antikoerper, HNSPC antikoerper, KCNA11 antikoerper, KV7.2 antikoerper, KVEBN1 antikoerper, KQT2 antikoerper, Nmf134 antikoerper, mKQT2.3 antikoerper, mKQT2.4 antikoerper, zgc:171872 antikoerper, potassium voltage-gated channel subfamily Q member 2 antikoerper, potassium voltage-gated channel, subfamily Q, member 2 antikoerper, potassium voltage-gated channel subfamily KQT member 2 antikoerper, potassium voltage-gated channel, KQT-like subfamily, member 2a antikoerper, KCNQ2 antikoerper, Kcnq2 antikoerper, LOC100537363 antikoerper, kcnq2a antikoerper
    Hintergrund
    The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by KCNQ2 and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1).
    Molekulargewicht
    93 kDa (MW of target protein)
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