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CACNB4 Antikörper (Middle Region)

CACNB4 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN633638
  • Target Alle CACNB4 Antikörper anzeigen
    CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
    Bindungsspezifität
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 25
    • 16
    • 14
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 22
    • 4
    • 1
    Kaninchen
    Klonalität
    • 25
    • 2
    Polyklonal
    Konjugat
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CACNB4 Antikörper ist unkonjugiert
    Applikation
    • 15
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    CACNB4 antibody was raised against the middle region of CACNB4
    Aufreinigung
    Affinity purified
    Immunogen
    CACNB4 antibody was raised using the middle region of CACNB4 corresponding to a region with amino acids GVPDPGTGASSGTRTPDVKAFLESPWSLDPASASPEPVPHILASSRQWDP
    Top Product
    Discover our top product CACNB4 Primärantikörper
  • Applikationshinweise
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    Kommentare

    CACNB4 Blocking Peptide, catalog no. 33R-3649, is also available for use as a blocking control in assays to test for specificity of this CACNB4 antibody

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CACNB4 antibody in PBS
    Konzentration
    Lot specific
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
    Andere Bezeichnung
    CACNB4 (CACNB4 Produkte)
    Synonyme
    CAB4 antikoerper, CACNLB4 antikoerper, EA5 antikoerper, EIG9 antikoerper, EJM antikoerper, EJM4 antikoerper, EJM6 antikoerper, 3110038O15Rik antikoerper, Cchb4 antikoerper, lethargic antikoerper, lh antikoerper, CACNB4 antikoerper, cacnb4.2 antikoerper, calcium voltage-gated channel auxiliary subunit beta 4 antikoerper, calcium channel, voltage-dependent, beta 4 subunit antikoerper, calcium channel, voltage-dependent, beta 4a subunit antikoerper, CACNB4 antikoerper, Cacnb4 antikoerper, cacnb4.1 antikoerper, cacnb4 antikoerper, cacnb4a antikoerper
    Hintergrund
    CACNB4 is a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. CACNB4 plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME).
    Molekulargewicht
    50 kDa (MW of target protein)
    Pathways
    cAMP Metabolic Process, Skeletal Muscle Fiber Development
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