STAT2 Antikörper (Biotin)

Produktnummer ABIN6297844

Produktdetails anti-STAT2 Antikörper (Biotin)

Target: STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STAT2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Verwendungszweck: Rabbit anti-Human Phosphorylated STAT2 Antibody [+Biotin],

Immunogen: This antibody was produced from antiserum of rabbits immunized with a synthetic immunogen. The IgG fraction was purified by Protein A affinity chromatography.

Anwendungsinformationen

Applikationshinweise: ELISA (recommended work dilution= 1:320,000)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Product is supplied as a powder obtained from lyophilization of purified antibody in citric acid solution . Reconstitute the antibody with diluent buffer to a final concentration of 1 mg/mL.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: -20°C

Details zu STAT2

Target: STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))

Andere Bezeichnung: Signal transducer and activator of transcription 2 (STAT2 Produkte)

Synonyme: wu:fj84d07 antikoerper, p113 antikoerper, stat2 antikoerper, 1600010G07Rik antikoerper, AW496480 antikoerper, ISGF-3 antikoerper, P113 antikoerper, STAT113 antikoerper, signal transducer and activator of transcription 2 antikoerper, AGAP000099-PA antikoerper, stat2 antikoerper, STAT2 antikoerper, Stat2 antikoerper

Hintergrund:

Target Description: Signal transducer and activator of transcription 2  is a  protein  that in humans is encoded by the STAT2  gene.The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (IRF9), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.STAT2-PY is the phosphorylated form of STAT2 protein.

Gene Symbol: STAT2

Gen-ID: 6773

UniProt: P52630

Pathways: JAK-STAT Signalweg, Hepatitis C, CXCR4-mediated Signaling Events