STAT6 Antikörper (Biotin)

Produktnummer ABIN6297842

Produktdetails anti-STAT6 Antikörper (Biotin)

Target: STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STAT6 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Verwendungszweck: Rabbit anti-Human Phosphorylated STAT6 Antibody [+Biotin],

Immunogen: This antibody was produced from antiserum of rabbits immunized with a synthetic immunogen. The IgG fraction was purified by Protein A affinity chromatography.

Anwendungsinformationen

Applikationshinweise: ELISA (recommended work dilution= 1:8,000)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Product is supplied as a powder obtained from lyophilization of purified antibody in citric acid solution . Reconstitute the antibody with diluent buffer to a final concentration of 1 mg/mL.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: -20°C

Details zu STAT6

Target: STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))

Andere Bezeichnung: Signal transducer and activator of transcription 6 (STAT6 Produkte)

Synonyme: D12S1644 antikoerper, IL-4-STAT antikoerper, STAT6B antikoerper, STAT6C antikoerper, signal transducer and activator of transcription 6 antikoerper, signal transducer and activator of transcription 6-like antikoerper, STAT6 antikoerper, Stat6 antikoerper, LOC100859543 antikoerper

Hintergrund:

Target Description: STAT6  is a human  gene. The  protein  encoded by this gene is a member of the  STAT family  of  transcription factors.In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2), expression of cell surface markers, and class switch of immunoglobulins.Phospho-STAT6-PY is the phosphorylated form of STAT6 protein.

Gene Symbol: STAT6

Gen-ID: 6778

UniProt: P42226

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response