STAT6 Antikörper (Biotin)
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- Target Alle STAT6 Antikörper anzeigen
- STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser STAT6 Antikörper ist konjugiert mit Biotin
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Applikation
- ELISA
- Verwendungszweck
- Rabbit anti-Human Phosphorylated STAT6 Antibody [+Biotin],
- Immunogen
- This antibody was produced from antiserum of rabbits immunized with a synthetic immunogen. The IgG fraction was purified by Protein A affinity chromatography.
- Top Product
- Discover our top product STAT6 Primärantikörper
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- Applikationshinweise
- ELISA (recommended work dilution= 1:8,000)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- Product is supplied as a powder obtained from lyophilization of purified antibody in citric acid solution . Reconstitute the antibody with diluent buffer to a final concentration of 1 mg/mL.
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- -20°C
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- Target
- STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
- Andere Bezeichnung
- Signal transducer and activator of transcription 6 (STAT6 Produkte)
- Synonyme
- D12S1644 antikoerper, IL-4-STAT antikoerper, STAT6B antikoerper, STAT6C antikoerper, signal transducer and activator of transcription 6 antikoerper, signal transducer and activator of transcription 6-like antikoerper, STAT6 antikoerper, Stat6 antikoerper, LOC100859543 antikoerper
- Hintergrund
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Target Description: STAT6 is a human gene. The protein encoded by this gene is a member of the STAT family of transcription factors.In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2), expression of cell surface markers, and class switch of immunoglobulins.Phospho-STAT6-PY is the phosphorylated form of STAT6 protein.
Gene Symbol: STAT6
- Gen-ID
- 6778
- UniProt
- P42226
- Pathways
- JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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