CD36 Antikörper
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- Target Alle CD36 Antikörper anzeigen
- CD36
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD36 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
- Verwendungszweck
- Mouse anti-Human CD36 Antibody [Sodium Azide Free]
- Spezifität
- Cell surface
- Aufreinigung
- Stimulated human leukocytes were used as the immunogen for the CD36 antibody.
- Immunogen
- Stimulated human leukocytes were used as the immunogen for the CD36 antibody.
- Top Product
- Discover our top product CD36 Primärantikörper
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- Applikationshinweise
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Functional Activity (Order SAF formulation) (1)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- In 1X PBS, BSA free, sodium azide free
- Konservierungsmittel
- Azide free
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Target
- CD36
- Andere Bezeichnung
- Platelet glycoprotein 4 (CD36 Produkte)
- Synonyme
- BDPLT10 antikoerper, CHDS7 antikoerper, FAT antikoerper, GP3B antikoerper, GP4 antikoerper, GPIV antikoerper, PASIV antikoerper, SCARB3 antikoerper, Fat antikoerper, Scarb3 antikoerper, GPIIIB antikoerper, PAS-4 antikoerper, zgc:92513 antikoerper, CD36 molecule antikoerper, CD36 molecule (thrombospondin receptor) antikoerper, CD36 antikoerper, Cd36 antikoerper, cd36 antikoerper
- Hintergrund
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Target Description: CD36 binds to collagen, thrombospondin, anionic phospholipids and oxidized low-density lipoprotein (oxLDL). May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic effects. As a coreceptor for TLR4-TLR6 heterodimer, promotes inflammation in monocytes/macrophages. Upon ligand binding, such as oxLDL or amyloid-beta 42, rapidly induces the formation of a heterodimer of TLR4 and TLR6, which is internalized and triggers inflammatory response, leading to NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. [UniProt]
Gene Symbol: CD36///GP3B///GP4
- Gen-ID
- 948
- UniProt
- P16671
- Pathways
- TLR Signalweg, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteine
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