VWF Antikörper (AA 1815-1939)

Produktnummer ABIN6294346

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch VWF in IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für VWF Antikörper (AA 1815-1939) (ABIN6294346)

Target: VWF (Von Willebrand Factor (VWF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VWF Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-VWF Antikörper

Bindungsspezifität: AA 1815-1939

Verwendungszweck: Rabbit anti-Human Recombinant von Willebrand Factor / vWFAntibody [IHC only]

Spezifität: Cytoplasmic

Aufreinigung: Amino acids 1815-1939 from the human protein were used as the immunogen for this recombinant vWF antibody.

Immunogen: Amino acids 1815-1939 from the human protein were used as the immunogen for this recombinant vWF antibody.

Anwendungsinformationen

Applikationshinweise: Prediluted IHC only format: incubate for 30 min at RT (1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, For IHC use only

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu VWF

Target: VWF (Von Willebrand Factor (VWF))

Andere Bezeichnung: von Willebrand factor ]

Hintergrund:

Target Description: von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

Gene Symbol: VWF///F8VWF

Gen-ID: 7450

UniProt: P04275