PTPN13 Antikörper
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- Target Alle PTPN13 Antikörper anzeigen
- PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PTPN13 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human PTPN13
- Isotyp
- IgG
- Top Product
- Discover our top product PTPN13 Primärantikörper
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- Applikationshinweise
- WB 1:500 - 1:2000
- Kommentare
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Present in most tissues with the exception of the liver and skeletal muscle, Most abundant in lung, kidney and fetal brain
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))
- Andere Bezeichnung
- PTPN13 (PTPN13 Produkte)
- Synonyme
- FAP-1 antikoerper, PNP1 antikoerper, PTP-BAS antikoerper, PTP-BL antikoerper, PTP1E antikoerper, PTPL1 antikoerper, PTPLE antikoerper, hPTP1E antikoerper, PTPN13 antikoerper, AI324989 antikoerper, Ptpri antikoerper, RIP antikoerper, Ptp-bl antikoerper, ptp antikoerper, wu:fb50g04 antikoerper, zgc:162319 antikoerper, protein tyrosine phosphatase, non-receptor type 13 antikoerper, tyrosine-protein phosphatase non-receptor type 13 antikoerper, PTPN13 antikoerper, LOC100540743 antikoerper, ptpn13 antikoerper, Ptpn13 antikoerper
- Hintergrund
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.
- Molekulargewicht
- 276.906 kDa
- Gen-ID
- 5783
- UniProt
- Q12923
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