P2RY12 Antikörper

Produktnummer ABIN6293326

Produktdetails anti-P2RY12 Antikörper

Target: P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser P2RY12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human P2RY12

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Kommentare:

Highly expressed in the platelets, lower levels in the brain, Lowest levels in the lung, appendix, pituitary and adrenal gland, Expressed in the spinal cord and in the fetal brain

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu P2RY12

Target: P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))

Andere Bezeichnung: P2RY12 (P2RY12 Produkte)

Synonyme: 2900079B22Rik antikoerper, 4921504D23Rik antikoerper, P2Y12 antikoerper, ADPG-R antikoerper, BDPLT8 antikoerper, HORK3 antikoerper, P2T(AC) antikoerper, P2Y(12)R antikoerper, P2Y(AC) antikoerper, P2Y(ADP) antikoerper, P2Y(cyc) antikoerper, SP1999 antikoerper, P2y12 antikoerper, purinergic receptor P2Y, G-protein coupled 12 antikoerper, purinergic receptor P2Y12 antikoerper, P2ry12 antikoerper, P2RY12 antikoerper

Hintergrund: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.

Molekulargewicht: 39.439 kDa

Gen-ID: 64805

UniProt: Q9H244