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ITGB3BP Antikörper

ITGB3BP Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6293028
  • Target Alle ITGB3BP Antikörper anzeigen
    ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))
    Reaktivität
    • 23
    • 4
    • 3
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 21
    • 2
    Kaninchen
    Klonalität
    • 21
    • 2
    Polyklonal
    Konjugat
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ITGB3BP Antikörper ist unkonjugiert
    Applikation
    • 12
    • 8
    • 7
    • 2
    Immunohistochemistry (IHC)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human ITGB3BP
    Isotyp
    IgG
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  • Applikationshinweise
    IHC 1:50 - 1:200
    Kommentare

    Widely expressed, Expressed in spleen, thymus, prostate, ovary, small intestine and white blood cells, Highly expressed in testis and colon, Isoform 4 is expressed in platelets, lymphocytes and granulocytes

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20C. Avoid freeze / thaw cycles.
  • Target
    ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))
    Andere Bezeichnung
    ITGB3BP (ITGB3BP Produkte)
    Synonyme
    CENP-R antikoerper, CENPR antikoerper, HSU37139 antikoerper, NRIF3 antikoerper, TAP20 antikoerper, 4930471O16Rik antikoerper, AU022583 antikoerper, integrin subunit beta 3 binding protein antikoerper, integrin beta 3 binding protein (beta3-endonexin) antikoerper, ITGB3BP antikoerper, Itgb3bp antikoerper
    Hintergrund
    This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
    Molekulargewicht
    20.194 kDa
    Gen-ID
    23421
    UniProt
    Q13352
    Pathways
    Neurotrophin Signalübertragung
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